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Xpress™ Mouse PD1 Over-expressing Cell Line (293T)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Mouse PD1 Over-expressing Cell Line (293T)
Species

Mouse
Cat.No

ABC-X0109C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T

Description

Xpress™ Mouse PD1 over-expressing cell line (293T) is a genetically engineered model derived from selected 293T parental cell line based on customers’ requirement. Mouse PD1 (Pdcd1) overexpression cell line is generated by stable integration of exogenous mouse PD1 gene into 293T host cells using our optimized transduction of lentiviral vectors.
Target
PD1 is an immune checkpoint receptor expressed on activated T cells and plays a critical role in T cell exhaustion and tumor immune escape. It interacts with ligands PD-L1 and PD-L2 to suppress T cell activity. AcceGen provides checkpoint molecule overexpression models for cancer immunotherapy research. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Xpress™ Mouse PD1 over-expressing cell line (293T) serves as a powerful model for evaluating checkpoint blockade therapies in murine models. It supports CAR-T engineering, antibody development, and mechanistic studies of PD1 signaling.

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