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Xpress™ Rat CD73 Over-expressing Cell Line (CHOK1)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Rat CD73 Over-expressing Cell Line (CHOK1)
Species

Rat
Cat.No

ABC-X0132C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1

Description

Xpress™ Rat CD73 over-expressing cell line is a genetically engineered model derived from selected CHOK1 parental cell line based on customers’ requirement. Rat CD73 overexpression cell line is generated by stable integration of exogenous rat CD73 (Nt5e) into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
CD73 (ecto-5′-nucleotidase, Nt5e) is an enzyme that catalyzes the conversion of extracellular AMP to adenosine, playing a key role in immunosuppression and tumor immune evasion. It is involved in purinergic signaling and contributes to the formation of an immunosuppressive tumor microenvironment. CD73 overexpression has been observed in various cancers, including breast, colorectal, and prostate cancer. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Rat CD73 CHOK1 Overexpression Cell Line provides a robust model for studying CD73-mediated adenosine signaling and its immunoregulatory roles. It is suitable for evaluating small molecule inhibitors or antibodies targeting CD73 in preclinical screening and immunotherapy development.

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