For research use only
| Cat No. | ABC-X0357C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Rhesus |
| Host Cell | CHOK1 |
| Source Organ | Ovary |
| Disease | Normal |
| Storage | Liquid Nitrogen |
CHOK1 cells stably expressing Rhesus Muc1, suitable for comparative glycoprotein biology, mucosal immunity research, and preclinical cancer model studies.
Muc1 CHOK1 Overexpression Cell Line is a genetically engineered model derived from selected Chinese hamster ovary (CHOK1) parental cell line based on customers’ requirement. Muc1 CHOK1 overexpression cell line is generated by stable integration of exogenous rhesus Muc1 into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The Muc1 gene encodes a membrane-bound mucin glycoprotein that is highly expressed on epithelial tissues and plays roles in lubrication and cell signaling. In rhesus macaques, Muc1 shows conserved functions in barrier protection and immune regulation. Overexpression is associated with tumor progression, immune evasion, and chemoresistance in various epithelial cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Rhesus |
| Cat.No | ABC-X0357C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Ovary |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | CHOK1 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The Muc1 CHOK1 Overexpression Cell Line serves as a powerful tool to investigate Muc1-associated tumor biology and glycosylation-dependent signaling. This model enables mechanistic studies of immune evasion, metastasis, and targeted immunotherapy in preclinical cancer research. It is utilized for high-throughput screening of Muc1-targeted drugs, antibodies, and CAR-T platforms.