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| Product Code | 8305c; 8305-C; 8305C_1 |
| Species | Human |
| Cat.No | ABC-TC443S |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Thyroid |
| Storage | Liquid Nitrogen |
| Product Type | Human Thyroid Cancer Cell Lines |
8305C is a human thyroid carcinoma cell line that was originally isolated from the primary tumor of a 67-year-old female patient with primary thyroid cancer. 8305C exhibits epithelial-like morphology and adherent culture properties. Sequence analysis confirmed a specific mutation in the p53 gene, with a C:G to T:A transition at the first base of codon 273.
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The 8305C cell line is a model for investigating gene mutations involved in thyroid carcinoma, particularly in undifferentiated forms. It is used to examine molecular mechanisms driving malignant transformation and progression. Notably, its association with p53 mutations provides insight into thyroid cancer development, making it a valuable tool for studying cancer genetics and targeted therapy.
