For research use only
| Cat No. | ABC-TC0038 |
| Product Type | Human Kidney Cancer Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Kidney |
| Disease | Adenocarinoma |
| Product Code | ACHN cell, ACHN cell line |
ACHN Renal Adenocarcinoma Cells are pleural effusion-derived and support renal cancer studies, IFN response, and drug resistance mechanisms.
ACHN cell line is human epithelial tumor cell line derived from the pleural effusion of a 22-year-old male patient diagnosed with metastatic renal adenocarcinoma. The cell line exhibits adherent growth with epithelial-like morphology and forms cobblestone-shaped monolayers under standard culture conditions. ACHN cells are particularly valuable for studying metastatic processes, as they originated from a secondary tumor site while retaining characteristics of primary renal carcinoma. Karyotypic analyses reveal complex chromosomal abnormalities associated with renal cell carcinoma, including loss of 3p and gain of 5q regions. ACHN expresses epithelial markers and demonstrates responsiveness to growth-inhibitory effects of human interferons. The line is tumorigenic in immunodeficient mice and widely used in metastasis modeling, drug testing, and cytokine signaling research. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | ACHN cell, ACHN cell line |
| Species | Human |
| Cat.No | ABC-TC0038 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Kidney |
| Disease | Adenocarinoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Kidney Cancer Cell Lines |
ACHN is widely used as a model for studying metastatic renal cell carcinoma (RCC), providing insights into tumor progression, epithelial-to-mesenchymal transition (EMT), and drug response mechanisms. Its origin from a metastatic pleural lesion makes it ideal for in vitro and in vivo modeling of RCC dissemination. ACHN is also valuable in evaluating cytokine signaling, particularly interferon-mediated antiproliferative effects. Researchers commonly use this line in compound screening, immunotherapy development, and angiogenesis-related studies. Its genetic and phenotypic stability supports consistent assay performance in preclinical and translational research targeting advanced kidney cancers and therapy resistance mechanisms.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
