For research use only
| Cat No. | ABC-TC0057 |
| Product Type | Human Uterine Cancer Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Product Code | AV 3; AV-3 |
The AV3 cell line is a human choroidal melanoma model used for ocular cancer research, signaling pathway studies, and drug screening in vitro.
AV3 is a human epithelial tumor cell line originally established from normal amnion tissue but later found to exhibit cervical carcinoma characteristics. The line acquired multiple chromosomal abnormalities, including the presence of HeLa-specific marker chromosomes, suggesting cross-contamination or transformation. AV3 cells exhibit adherent growth and epithelial morphology. Despite its initial classification as amniotic in origin, AV3 behaves like cervical carcinoma cells and is classified as tumorigenic. The line displays high susceptibility to poliovirus type 1 and other human viruses and is commonly used in virology, cytopathogenicity, and virus–host interaction studies. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | AV 3; AV-3 |
| Species | Human |
| Cat.No | ABC-TC0057 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Uterine Cancer Cell Lines |
AV3 cells are widely used in virology research for their high susceptibility to poliovirus and related pathogens. They serve as in vitro models for virus entry, replication, and cytopathic effects in epithelial-like tumor cells. Their partial HeLa-like genome enables comparative studies on viral tropism and host-pathogen interactions. AV3 also supports DNA/RNA tumor virus studies, vaccine development, viral titration assays, and immune response analysis, offering stable growth and strong virus responsiveness for translational virus research.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
