For research use only
| Cat No. | ABC-TC0058 |
| Product Type | Human Gastric Cancer Cell Lines |
| Cell Type | Epithelial-like |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lymph Node |
| Disease | Gastric Cancer |
| Product Code | AZ 521; AZ521 |
AZ-521, a human gastric cancer cell line, supports studies of gastric carcinoma pathogenesis, drug resistance, and cell proliferation assays.
AZ-521 is a human epithelial-like tumor cell line isolated from a lymph node metastasis of a male patient.. The cells exhibit polygonal epithelial morphology, adherent growth, and express gastrointestinal epithelial markers. AZ-521 demonstrates stable proliferation in vitro and has been widely used in gastrointestinal cancer studies. Karyotype analysis reveals a hyperdiploid chromosomal profile with structural abnormalities consistent with intestinal adenocarcinoma. While its classification shifted from gastric to duodenal carcinoma, AZ-521 remains relevant for studies of gastrointestinal tumorigenesis, epithelial transport, and drug absorption. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | AZ 521; AZ521 |
| Species | Human |
| Cat.No | ABC-TC0058 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial-like |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lymph Node |
| Disease | Gastric Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Gastric Cancer Cell Lines |
AZ-521 is frequently employed in gastrointestinal cancer research, particularly in studies involving epithelial polarity, mucosal barrier function, and tumorigenic signaling pathways. Despite its corrected identity as a HuTu 80 derivative, AZ-521 remains relevant for investigating small intestinal adenocarcinoma mechanisms. The line is useful in assays modeling epithelial transport, nutrient absorption, and interactions with enteric pathogens or therapeutic agents. It is applied in comparative studies of upper gastrointestinal cancers and in screening compounds targeting intestinal epithelial tumors. AZ-521’s consistent epithelial phenotype, tumorigenicity in xenografts, and stable gene expression profile support its use in preclinical cancer biology, epithelial physiology, and pharmacological screening.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
