Tumor Cell Lines

B-23

  • For research use only

Cat No.

ABC-TC0063

Product Type

Rat Nerve Tumors Cell Lines

Species

Rat – BD-1X Rat

Growth Conditions

37 ℃, 5% CO2

Disease

Malignant Glioma

Product Code

B23, B 23, b-23

Tumorigenecity: Isoenzyme: Histopathology: astrocytomaSubculture: Split ratio: Media change: Reverse transcritase: Production

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Description

B-23 is a rat glioma-derived tumor cell line established from a malignant astrocytoma in BD-1X rats. It exhibits classical astrocytic morphology with elongated, multipolar cells and adherent monolayer growth under standard in vitro conditions. Histopathological analysis confirms high-grade astrocytoma features, including pleomorphism, mitotic activity, and nuclear atypia. B-23 demonstrates tumorigenicity when transplanted into syngeneic rats, forming aggressive intracranial or subcutaneous tumors with infiltrative behavior. The line expresses glial fibrillary acidic protein (GFAP), S100, and vimentin. B-23 is widely used for studying astrocytoma progression, neural invasion, and glioma immunology.The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

B23, B 23, b-23

Species

Rat – BD-1X Rat

Cat.No

ABC-TC0063

Product Category

Tumor Cell Lines

Size/Quantity

1 vial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Disease

Malignant Glioma

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Rat Nerve Tumors Cell Lines

Application

  • B-23 is an effective model for malignant glioma research, particularly for studies focused on astrocytoma biology, immune evasion, and therapeutic resistance. Its rat origin allows use in syngeneic BD-1X models, enabling immunocompetent glioma investigations. B-23 supports in vitro analysis of glioma cell proliferation, migration, invasion under defined B-23 growth conditions, and can be used in orthotopic or ectopic tumor implantation studies. It is ideal for screening chemotherapeutics, radiation sensitizers, and immunotherapies targeting high-grade astrocytomas. The line’s glial marker expression and reproducible tumorigenicity provide a robust platform for elucidating glioma progression and testing new treatment strategies in translational neuro-oncology research.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Inquiring B-23

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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