Primary Cells

BALB/c Mouse Bone Marrow Neutrophils

  • For research use only

Cat No.

ABC-TC3060

Product Type

Mouse Primary Cells

Cell Type

Neutrophil

Species

BALB/c Mouse

Growth Conditions

37 ℃, 5% CO2

Source Organ

Bone Marrow

Disease

Normal

Storage

Liquid Nitrogen

Mouse bone marrow neutrophils (MBMNEUCs) are derived from the tibias and femurs of pathogen-free laboratory adult mice.

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Description

BALB/c Mouse Bone Marrow Neutrophils are freshly isolated primary immune cells obtained from the bone marrow of BALB/c mice. As a key component of the innate immune system, neutrophils are short-lived, polymorphonuclear leukocytes that play a crucial role in the early defense against pathogens through mechanisms like phagocytosis, degranulation, and the generation of neutrophil extracellular traps (NETs). These cells are non-proliferative in vitro and are typically characterized by high expression of surface markers such as Ly6G and CD11b. Neutrophils from BALB/c mice are widely used to study inflammation, infection, and autoimmune mechanisms due to the strain’s distinct immune response profile. These primary neutrophils cannot be passaged or subcultured due to their terminally differentiated state. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

BALB/c Mouse Bone Marrow Neutrophils, BALB/c BMNs, BALB BM Neutrophils

Species

BALB/c Mouse

Cat.No

ABC-TC3060

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Neutrophil

Growth Mode

Suspension

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Bone Marrow

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Mouse Primary Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • BALB/c Mouse Bone Marrow Neutrophils serve as a valuable model for studying acute and chronic inflammatory processes, including sepsis, rheumatoid arthritis, and pulmonary inflammation. In vitro, they are employed to evaluate neutrophil activation pathways, cytokine responses, and drug screening for anti-inflammatory agents, making them particularly relevant for BALB/c bone marrow cell signaling studies. Their well-defined phenotype makes them ideal for immunological assays, flow cytometry, and functional studies of innate immunity. These neutrophils also facilitate investigations into ROS production, chemotaxis, and NET formation, enhancing the understanding of innate immune mechanisms and therapeutic target validation.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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