For research use only
| Cat No. | ABC-TC3060 |
| Product Type | Mouse Primary Cells |
| Cell Type | Neutrophil |
| Species | BALB/c Mouse |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Bone Marrow |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Mouse bone marrow neutrophils (MBMNEUCs) are derived from the tibias and femurs of pathogen-free laboratory adult mice.
BALB/c Mouse Bone Marrow Neutrophils are freshly isolated primary immune cells obtained from the bone marrow of BALB/c mice. As a key component of the innate immune system, neutrophils are short-lived, polymorphonuclear leukocytes that play a crucial role in the early defense against pathogens through mechanisms like phagocytosis, degranulation, and the generation of neutrophil extracellular traps (NETs). These cells are non-proliferative in vitro and are typically characterized by high expression of surface markers such as Ly6G and CD11b. Neutrophils from BALB/c mice are widely used to study inflammation, infection, and autoimmune mechanisms due to the strain’s distinct immune response profile. These primary neutrophils cannot be passaged or subcultured due to their terminally differentiated state. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | BALB/c Mouse Bone Marrow Neutrophils, BALB/c BMNs, BALB BM Neutrophils |
| Species | BALB/c Mouse |
| Cat.No | ABC-TC3060 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Neutrophil |
| Growth Mode | Suspension |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Bone Marrow |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Primary Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
BALB/c Mouse Bone Marrow Neutrophils serve as a valuable model for studying acute and chronic inflammatory processes, including sepsis, rheumatoid arthritis, and pulmonary inflammation. In vitro, they are employed to evaluate neutrophil activation pathways, cytokine responses, and drug screening for anti-inflammatory agents, making them particularly relevant for BALB/c bone marrow cell signaling studies. Their well-defined phenotype makes them ideal for immunological assays, flow cytometry, and functional studies of innate immunity. These neutrophils also facilitate investigations into ROS production, chemotaxis, and NET formation, enhancing the understanding of innate immune mechanisms and therapeutic target validation.
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