Bovine Cartilage Cells

Description

Bovine Cartilage Cells are isolated from the bovine articular cartilage tissue. Morphologically, these cells are round or oval, with relatively small cell size and round and centrally located nuclei. When cultured in vitro, cells mostly grow as an adherent monolayer on standard tissue culture surfaces. With increasing culture duration and cell density, the cell morphology gradually becomes flatter. Functionally, bovine cartilage cells maintain the mechanical load capacity of the joint by synthesizing proteoglycans and collagen networks, while secreting both matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) to balance extracellular matrix degradation and synthesis, ensuring cartilage metabolic homeostasis. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.