For research use only
| Cat No. | ABC-TC0088 |
| Product Type | Human Uterine Cancer Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Cervix |
| Product Code | HeLa (BU-25); HeLa BU25; HeLa Bu25; HeLa/BU-25; HeLa(BU25); HeLa TK- (BU 25); BU25 TK-; Bu25TK- |
Human cervical carcinoma. HeLa derivative rendered TK- by selection in BUdR.
Bu25 TK⁻ is a human cervical carcinoma cell line derived from HeLa cells (African-American, female, age ~30 years) and genetically modified to be thymidine kinase deficient (TK⁻) through selection in bromodeoxyuridine (BUdR). These epithelial-like cells exhibit adherent growth properties and retain an aneuploid karyotype typical of HeLa derivatives. The absence of functional TK activity makes Bu25 TK⁻ a valuable model for nucleotide metabolism and virology studies. There are no known viral infections beyond the endogenous HPV-18 . The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | HeLa (BU-25); HeLa BU25; HeLa Bu25; HeLa/BU-25; HeLa(BU25); HeLa TK- (BU 25); BU25 TK-; Bu25TK- |
| Species | Human |
| Cat.No | ABC-TC0088 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Cervix |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Uterine Cancer Cell Lines |
Bu25 TK− is well-suited for studies in nucleotide metabolism, antiviral screening, and selection assays based on TK⁻ systems, highlighting the BU25 TK scientific significance in molecular and cellular research. It has been successfully applied in transfection experiments, evaluation of drug sensitivity in TK-deficient contexts, and in DNA repair and gene therapy research. Its stable adherence and defined STR profile also facilitate repeatable studies in DNA repair, gene therapy, and viral vector research.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
