C57BL/6 Mouse Kidney Cells

Description

C57BL/6 Mouse Kidney Cells are primary cells isolated from the kidney tissue of pathogen-free laboratory mice, serving as a reliable model for molecular studies in mouse kidney. Following primary culture, these cells are cryopreserved. These cells originate from the functional compartments of the renal parenchyma, including glomerular and tubular structures, where they perform essential physiological functions such as glomerular filtration, tubular reabsorption, ion regulation, and endocrine activity. C57BL/6 mouse kidney cells lack intrinsic self-renewal capacity, with regeneration occurring through regional progenitor cells and dedifferentiation of surviving tubular epithelial cells after injury. Studies have demonstrated their involvement in acute kidney injury, diabetic nephropathy, polycystic kidney disease, and hypertension. For optimal performance, repeated freezing and thawing should be avoided during culture. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.