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C57BL/6 Mouse Primary Thymus Epithelial Cells

Product Name

C57BL/6 Mouse Primary Thymus Epithelial Cells

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Product Code

MTECs

Cat.No

ABC-TC5502

Species

C57BL/6 Mouse

Size/Quantity

1 vial

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

C57BL/6 mouse primary thymus epithelial cells are isolated from the thymus of newborn C57BL/6 mice, which is the most famous inbred mouse strain with reserved genetic basis for cancer research. C57BL/6 has been widely used in biomedical research as either a genetic background or a general purpose strain for spontaneous and induced mutant mice. As the main component of thymic stroma, thymus epithelium cells (TECs) affects T cell development and differentiation through the secretion of the thymic peptides by thymus epithelial cells. The process of T cell development is highly dependent on the communications between the developing T cells and thymus epithelial cells, which especially support the T cell development by providing cytokines, chemokines, lineage inductive ligands, selective self-antigens, cell surface molecules, and extracellular matrix elements.

 

Why choose C57BL/6 Mouse Primary Thymus Epithelial Cells from AcceGen?

AcceGen supports C57BL/6 mouse primary thymus epithelial cells with advanced techniques for primary cells. Our C57BL/6 mouse primary thymus epithelial cell has the best viability and plating efficiency. We guarantee to deliver C57BL/6 mouse primary thymus epithelial cells in a professional, safe, and quick way to ensure that every customer receives the best quality product.

Disease

Normal

Source Organ

Thymus

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

C57BL/6 mouse primary thymus epithelial cell is a useful cell line to investigate thymic activities, such as the secretion of thymus hormones and the development of thymocytes. Thymus epithelial cells also express MHC class II molecules on the surface, which are involved in the antigen presentation for an immune response. Considering the tight connection with thymocytes, TECs can be used in the research of immune system, such as identification of modulators in thymocyte development. For example, androgen receptor was identified in the immunohistochemical analysis and hormone-binding assay of thymic epithelial cells. C57BL/6 mouse primary thymus epithelial cells can also be used in some interesting trials, such as assessing the resistant to ionizing radiation.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Epithelial

Growth Mode

Adherent

Product Type

Mouse Primary Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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