C57BL/6 Mouse Spleen Endothelial Cells

Description

C57BL/6 Mouse Spleen Endothelial Cells, also known as Murine splenic endothelial primary cells and Mouse spleen vascular cells, are derived from the splenic vascular network of the C57BL/6 mouse. These cells line the blood vessels of the spleen and play important roles in regulating immune cell trafficking, maintaining vascular integrity, and responding to inflammatory signals. Spleen endothelial cells are involved in leukocyte adhesion, antigen transport, and cytokine signaling. Studies have shown their role in immune activation and tolerance, particularly during infection and autoimmune responses. Mouse spleen endothelial cells serve as an in vitro model for vascular-immune interactions within secondary lymphoid organs. These cells express characteristic endothelial markers including CD31 (PECAM-1), VE-cadherin (CD144), ICAM-1, and VCAM-1. Avoid repeated freeze-thaw cycles in vitro to maintain cell viability and function. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from mycoplasma, fungi, yeast, and bacteria.