C57BL/6 Mouse Splenic Fibroblasts

Description

C57BL/6 Mouse Splenic Fibroblasts are derived from stromal components of the spleen tissue in C57BL/6 mice. These fibroblasts contribute to extracellular matrix deposition and support the structural integrity of the splenic microenvironment. Following the isolation, the cells are cryopreserved at early passage. Spleen fibroblasts play roles in lymphocyte localization, tissue remodeling, and immune cell interactions. Studies have demonstrated their involvement in immune tolerance, stromal cell signaling, and inflammatory disease models. They express fibroblast markers vimentin. Mouse spleen fibroblasts are widely used in immunological and stromal-immune interaction studies. Avoid repeated freeze-thaw cycles in vitro to maintain cell viability and function. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from mycoplasma, fungi, yeast, and bacteria.