Canine Aortic Smooth Muscle Cells

Description

Canine Aortic Smooth Muscle Cells are derived from the tunica media of the aortic wall in dogs. These dog aortic SMCs primary cells originate from the canine ascending aorta smooth muscle and exhibit contractile and synthetic properties that contribute to the regulation of vascular tone, extracellular matrix production, and arterial remodeling. These cells display typical spindle-shaped morphology and express smooth muscle marker α-smooth muscle actin (α-SMA). Aortic smooth muscle cells play a central role in vascular homeostasis, atherogenesis, and response to hemodynamic stress. Studies have shown their involvement in arterial hypertension, aneurysm formation, and vascular calcification. Canine aortic smooth muscle cells offer a relevant model for comparative cardiovascular research and drug screening. Avoid repeated freeze-thaw cycles in vitro to maintain cell viability and function. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from mycoplasma, fungi, yeast, and bacteria.