CD-1 Mouse Stomach Cells

Description

CD-1 Mouse Stomach Cells are primary cells isolated from the gastric tissue of healthy CD-1 mice. These cells include a heterogeneous population primarily composed of gastric epithelial cells, including parietal, chief, and mucous cells, each playing essential roles in digestive physiology. Following isolation, the cells are cryopreserved at early passages to preserve functionality and cellular identity. CD-1 Mouse Stomach Cells retain physiological activity related to acid secretion, pepsinogen production, and mucosal protection. In vitro, these cells exhibit epithelial morphology and form adherent monolayers. Studies have shown that gastric epithelial cells are pivotal in mucosal immunity and host defense against pathogens such as Helicobacter pylori. They also play a role in inflammatory disorders and the development of gastric metaplasia or carcinoma. The cells express key markers such as H⁺/K⁺-ATPase (parietal cells) and MUC5AC (mucous cells). These cells should not be subjected to repeated freeze-thaw cycles. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.