+1 862-686-2696
Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Nucleic Acid Kits
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Transfected Stable Cell Lines

CD19 Knockout Raji/Luciferase Cell Line

  • BSL

    1

  • 111
Request Your Custom Quote Today

Discover top-quality products tailored for scientific and medical research. Request a personalized quote today
to enhance your projects.

Get a Quote
  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Home | Transfected Stable Cell Lines | CD19 Knockout Raji/Luciferase Cell Line
Species

Human
Cat.No

ABC-RC056Y
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphoblast-like
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Burkitt’s Lymphoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Reporter Stable Cell Lines
Host Cell

Raji
Gene Info

CD19 / Luciferase

Description

CD19 Knockout Raji/Luciferase Cell Line is a genetically engineered B-lymphocyte model derived from Raji cells, featuring dual modifications: stable integration of luciferase (Luc) reporter gene and complete knockout of CD19 expression. This cell line maintains characteristic Raji cell morphology and growth properties while providing sensitive bioluminescence detection for in vivo tumor tracking. The CD19 knockout eliminates target expression for CD19-directed immunotherapies (including CAR-T cells and monoclonal antibodies), making it particularly valuable for studying therapy resistance mechanisms and developing alternative treatment strategies for B-cell malignancies. Cells exhibit stable luciferase expression across passages (<P20) with consistent proliferation rates, enabling reliable longitudinal studies in xenograft models. The cell line is rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, mycoplasma, Fungi, Yeast and Bacteria.

AcceGen Frozen Cells & Cell Lines 1 vial
View Product Image

Application

  • FOR RESEARCH USE ONLY

  • The CD19 Knockout Raji/Luciferase Cell Line is a genetically engineered B-lymphoma model featuring CD19 gene disruption (via CRISPR/Cas9) with stable luciferase reporter integration. This dual-modified system enables sensitive bioluminescence tracking of tumor progression while serving as an essential tool for studying CD19-independent mechanisms in B-cell malignancies and resistance to CD19-targeted therapies (e.g., CAR-T cells, blinatumomab). Maintain in RPMI-1640 with 10% FBS and appropriate antibiotics for reliable performance in xenograft studies and immunotherapy development applications.

  • Online Inquiry
  • Product Reviews

Inquiring CD19 Knockout Raji/Luciferase Cell Line

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button