Primary Cells

CD57 Mouse Neurons cortical

  • For research use only

Cat No.

ABC-TC3326

Product Type

Mouse Primary Cells

Cell Type

Neuron

Species

CD57 Mouse

Growth Conditions

37 ℃, 5% CO2

Source Organ

Brain

Disease

Normal

Storage

Liquid Nitrogen

The tissue of the central nervous system is made up of two classes of cells that may be broadly categorized as neurons and glia.

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Description

CD57 Mouse Cortical Neurons are primary neuronal cells isolated from the cerebral cortex of C57BL/6 mice. These cells are predominantly post-mitotic excitatory neurons with a small fraction of glial progenitors. C57BL/6 cortical neurons are highly sensitive to environmental cues and are widely used to model neuronal development, synaptic transmission, and neurodegeneration. Cortical neurons exhibit characteristic pyramidal morphology with extensive neurite outgrowth in culture. These neurons express key neuronal markers such as MAP2, βIII-tubulin (Tuj1), and NeuN, and show spontaneous electrical activity in vitro. Primary cortical neurons are non-proliferative, and multiple passages are not recommended. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

CD57 Mouse Neurons Cortical, Mouse Cortical Neurons, Cortical Neurons, Neurons, CNs, CD57 CNs

Species

CD57 Mouse

Cat.No

ABC-TC3326

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Neuron

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Brain

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Mouse Primary Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • CD57 Mouse Cortical Neurons serve as a robust in vitro platform for dissecting neurodevelopment, synaptic plasticity, and CD57 cortical brain functions. They are particularly valuable for studying Alzheimer’s disease, epilepsy, and ischemic brain injury. For example, cortical neurons exposed to amyloid-β peptides recapitulate key features of neurodegeneration, enabling the exploration of therapeutic compounds and signaling pathways involved in neuronal death. These neurons are also ideal for electrophysiological studies and high-content screening of neuroprotective agents.

Citation

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