For research use only
| Cat No. | ABC-TC3329 |
| Product Type | Mouse Primary Cells |
| Cell Type | Neuron |
| Species | CD57 Mouse |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Brain |
| Disease | Normal |
| Storage | Liquid Nitrogen |
The tissue of the central nervous system is made up of two classes of cells that may be broadly categorized as neurons and glia.
CD57 Mouse Neurons Raphe are primary neuronal cells isolated from the dorsal raphe nucleus of C57BL/6 mice. The cells are harvested from postnatal mice under sterile conditions and cryopreserved shortly after isolation to maintain viability and functional integrity. These neurons exhibit typical bipolar or multipolar morphology, extending fine neurites in culture. They play a central role in mood disorders such as depression and anxiety and are involved in neurodegenerative diseases including Parkinson’s and Alzheimer’s. These cells do not proliferate in vitro and are not suitable for passaging. Repeated freeze-thaw cycles are discouraged to preserve cellular activity. These neurons express serotonin transporter (SERT) and tryptophan hydroxylase (TPH2), key markers of serotonergic neurons, as confirmed by immunocytochemical staining. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | CD57 Mouse Neurons Raphe, Mouse Raphe Neurons, Raphe Neurons, Serotonergic Neurons, RNs, CD57 RNs |
| Species | CD57 Mouse |
| Cat.No | ABC-TC3329 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Neuron |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Brain |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Primary Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
CD57 Mouse Neurons Raphe serve as a reliable in vitro model for studying serotonergic signaling pathways, antidepressant drug mechanisms, and stress-related neuroplasticity, and mouse stress resilience. They are particularly useful in modeling serotonergic dysregulation in mood disorders and can help identify therapeutic targets in psychiatric and neurodegenerative conditions.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).