For research use only
| Cat No. | ABC-TC0174 |
| Product Type | Human Melanoma Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lymph Node |
| Disease | Cutaneous Melanoma |
| Product Code | COLO-853, Human Melanoma Cell Line COLO-853, COLO 853, COLO853, COLO-0853, Metastatic Melanoma Cell Line, Tumor Biology Cells |
The COLO-853 cell line is a human colorectal carcinoma cell line ideal for cancer biology research and high-throughput drug screening studies.
COLO-853 is a human melanoma cell line derived from the right axilla lymph node of a 43 year old male with malignant melanoma, a highly aggressive form of skin cancer originating from melanocytes. This cell line exhibits typical epithelial-like morphology, characterized by adherent growth with polygonal or spindle-shaped cells that form monolayer clusters in culture. COLO-853 possesses an aneuploid karyotype with complex chromosomal aberrations, including deletions, translocations, and amplifications, which are common in advanced melanoma and contribute to its malignant phenotype. CD105 presented a strong expression in the cytoplasm of COLO-853, but was weakly expressed on the cell membrane. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | COLO-853, Human Melanoma Cell Line COLO-853, COLO 853, COLO853, COLO-0853, Metastatic Melanoma Cell Line, Tumor Biology Cells |
| Species | Human |
| Cat.No | ABC-TC0174 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lymph Node |
| Disease | Cutaneous Melanoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Melanoma Cell Lines |
COLO-853 is an important in vitro model widely used to study melanoma pathogenesis and metastatic behavior. It is commonly used to investigate the activation of key melanoma signaling pathways, including BRAF, NRAS, and MITF, and their role in tumor growth and metastasis. Analysis of GEN 853 further provides molecular insights into gene regulation and pathway activity, supporting mechanistic studies in melanoma research.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
