For research use only
| Cat No. | ABC-TC0190 |
| Product Type | Monkey Kidney Cell Lines |
| Cell Type | Fibroblast-like |
| Species | Cercopithecus Aethiops |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Kidney |
| Product Code | Cos-7; COS 7; Cos 7; COS7; Cos7; CV-1 in Origin Simian-7 |
COS-7 fibroblast-like cells from African green monkey kidney, SV40 immortalized, used for transfection and viral replication studies, virus-free.
COS-7 is an African green monkey (Cercopithecus aethiops) kidney fibroblast-like cell line derived by transformation of CV-1 cells with an origin-defective mutant of simian virus 40 (SV40). These cells display a fibroblast-like morphology and exhibit rapid and adherent growth on glass and plastic surfaces. COS-7 cells express the SV40 large T antigen, allowing episomal replication of transfected plasmids containing the SV40 origin of replication. Their stable karyotype and high transfection efficiency make them ideal for recombinant protein expression and gene function studies, particularly for transfection experiments, including the analysis of steroidogenic genes, steroid receptors, and the effects of steroids on gene expression. Although COS-7 cells are non-tumorigenic in immunodeficient mice, their SV40 transformation confers immortalization. The cells are rigorously tested to ensure they are free of contamination from mycoplasma, fungi, yeast and bacteria.
| Product Code | Cos-7; COS 7; Cos 7; COS7; Cos7; CV-1 in Origin Simian-7 |
| Species | Cercopithecus Aethiops |
| Cat.No | ABC-TC0190 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast-like |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Kidney |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Monkey Kidney Cell Lines |
COS-7 cells are critical models used in research. They are widely utilized for studying SV40 monkey viruses and serve as the commonly used mammalian transient expression host for research-scale protein production such as antibodies and cytokines. The fibroblastic-like growth characteristics of COS-7 cells, combined with their susceptibility to SV40, make them an excellent choice for transfection experiments involving DNA plasmids and mutations to the SV40 virus. Given the potential link between SV40 and human cancers, the continued use of COS-7 cells in SV40-related research provides insights into SV40-associated tumorigenesis.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
