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| Product Code | EL4NOB1; NOB-1 |
| Species | Mouse |
| Cat.No | ABC-TC0244 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Lymphoblast |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Blood |
| Disease | Lymphoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Lymphoma Cell Lines |
EL4.NOB-1 is a murine lymphoma cell line that was originally isolated from a specific strain of C57BL/6N mice. EL4.NOB-1 exhibits lymphoblast-like morphology and suspension culture properties. This cell line shows elevated expression of the IL-1 receptor and is resistant to TGF-β-induced growth arrest. EL4.NOB-1 also retains sensitivity to both autocrine stimulation and IL-1-induced inhibition of IL-2 production.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
EL4.NOB-1 enables immunology research focused on IL-1 receptor signaling pathways and immune modulation. It models cytokine production through IL-1-induced IL-2 secretion, supporting pharmacological assays using enzyme inhibitors targeting PKC, PKA, MAPK, PLA2, PI-PLC, and PC-PLC. The cell line facilitates cellular growth, autoinduction, and TGF-β resistance studies while investigating IL-1-induced IL-2 suppression. Additionally, it advances signaling pathway analysis of IL-1 receptor activation and molecular biology research characterizing immune signaling genes and proteins.
