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| Product Code | H1975; H-1975; NCIH1975 |
| Species | Human |
| Cat.No | ABC-TC521S |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lung |
| Disease | Adenocarinoma |
| Storage | Liquid Nitrogen |
| Product Type | Human Lung Cancer Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
H1975 is a widely used model in immuno-oncology and lung cancer research, particularly for investigating epidermal growth factor receptor (EGFR) mutation-driven tumorigenesis and TKI resistance mechanisms. Its dual EGFR mutations make it an ideal platform for preclinical evaluation of EGFR tyrosine kinase inhibitors and combination therapies aiding in the development of strategies to overcome this resistance. Additionally, they are employed in 3D cell culture models, xenograft models, and immune-oncology research to assess drug responses in a physiologically relevant context. Therefore, H1975 remains a cornerstone in development of potential therapeutic interventions for EGFR-mutant NSCLC.
