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HARA | ||||
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| Product Name | HARA | |||
| Price | Get Quote | |||
| Cat.No | ABC-TC0287 | Species | Human | |
| Size/Quantity | 1 vial | Biosafety Level | 1 | |
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description |
Why choose HARA from AcceGen? The HARA cell line boasts exceptional viability and quality, confirmed through STR analysis for precise identification. It maintains sterility while testing negative for mycoplasma, fungi, bacteria, and human pathogens, ensuring its reliability for various research applications. | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Application | FOR RESEARCH USE ONLY The HARA cell line’s significance lies in its potential applications, particularly in elucidating the interplay between PTHrP and IL-1 for hypercalcemia induction, owing to its expression of both factors. Moreover, its suitability for investigating bone metastasis is underscored by IL-1’s bone-resorbing activity and PTHrP’s pivotal role in bone metastasis formation, offering valuable insights into these complex biological processes. | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Product Type | Human Lung Cancer Cell Lines | |||
| Product Image |  | |||
HARA, also known as KCC-C1, is established from malignant pleural effusion of a patient with squamous cell lung carcinoma. These cells exhibit a distinctive trait of producing notable quantities of parathyroid hormone-related protein (PTHrP), as evidenced by both PTHrP RNA transcripts and substantial PTHrP secretion. Alongside PTHrP, the cell culture medium demonstrates a notable presence of interleukin 1 (IL-1). When transplanted into nude mice, KCC-C1 cells drive tumor formation coupled with hypercalcemia. The cell line is also known to induce extensive bone metastasis following injection into the heart chamber of nude mice.- ONLINE INQUIRY
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