For research use only
| Cat No. | ABC-TC0348 |
| Product Type | Human Uterine Cancer Cell Lines |
| Cell Type | Epithelial-like |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Uterus |
| Disease | Endometrial Adenocarinoma |
| Product Code | HEC59; Hec59 |
Endometrial carcinoma
HEC-59 is a human endometrial carcinoma cell line derived from a female patient. These cells grow as an adherent epithelial monolayer and exhibit moderate pleomorphism. HEC-59 is characterized by microsatellite instability (MSI). The cell line demonstrates tumorigenicity in xenograft models, making it a valuable tool for studying genomic instability, DNA repair deficiency, and the development of targeted therapies. It is widely used in preclinical studies on immunotherapy, chemoresistance, and cancer genome instability mechanisms. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | HEC59; Hec59 |
| Species | Human |
| Cat.No | ABC-TC0348 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial-like |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Uterus |
| Disease | Endometrial Adenocarinoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Uterine Cancer Cell Lines |
HEC-59 endometrial cancer cell line is a key model for studying mismatch repair (MMR) deficiency and microsatellite instability (MSI) in endometrial carcinoma. They are suited for investigating DNA repair mechanism disruptions, immune checkpoint modulation, and chemotherapeutic sensitivity in MSI-high cancers. This cell line is also used in precision oncology for screening targeted therapies and exploring genetic instability markers, offering valuable insights into personalized treatment strategies.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
