For research use only
| Cat No. | ABC-TC0362 |
| Product Type | Human Uterine Cancer Cell Lines |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Cervix |
| Disease | Cervix Cancer |
| Product Code | CVCL_3381 |
Species: human, Black female 31 years old; Tissue: cervix; Tumor: carcinoma, epitheloid
HeLa-432 is a cell line with a notable origin and a range of unique characteristics. It is derived from cervical cancer in a woman, sharing the same origin as the extensively studied HeLa cell line. These cells exhibit epithelial morphology, showing the distinct appearance typical of epithelial-like cells. They form adherent monolayers in culture. Genetically, HeLa-432 cells are transfected with an exon 4-deficient variant of ER-PBact cDNA (a human estrogen receptor cDNA). This genetic modification, under the control of the human β-actin promoter, confers resistance to the selective antibiotic G418. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | CVCL_3381 |
| Species | Human |
| Cat.No | ABC-TC0362 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Cervix |
| Disease | Cervix Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Uterine Cancer Cell Lines |
HeLa 432 cell line is valuable for studying estrogen receptor signaling and transcriptional regulation in a cancer context. Their modified receptor profile enables precise dissection of ligand-independent ER activities. They are suitable for drug response assays, stable transfection systems, and mechanistic research on hormone receptor pathways and targeted therapy development.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
