Bovine Corneal Endothelial Cells

Description

Bovine Corneal Endothelial Cells (BCEC) are isolated from bovine corneal tissue. Following the primary culture, these cells are cryopreserved. They express ZO-1, E-cadherin, and CK18. These cells are used to investigate corneal diseases such as Fuchs’ endothelial dystrophy and to explore potential treatment strategies, including corneal transplantation and cell-based regenerative therapies. Additionally, due to their ability to mimic human corneal endothelial cells, they serve as a valuable model for evaluating the efficacy and toxicity of drugs related to corneal health. In vitro, these cells exhibit limited proliferative capacity, and repeated freezing and thawing during culture should be avoided. The cells should be cultured according to AcceGen’s recommended culture conditions. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.