For research use only
| Cat No. | ABC-SC0124T |
| Product Type | Human iPSCs |
| Cell Type | Induced Pluripotent Stem Cell |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Normal |
| Storage | Liquid Nitrogen |
CHD8+/+ induced pluripotent stem cells (iPSC) were derived from skin fibroblasts
CHD8 has a role in chromatin dynamics, transcription and cell survival in which it interacts with p53 to regulate cell cycle genes. It has been associated with developmental disorders like ASD (autism spectrum disorders). CHD8+/+ induced pluripotent stem cells (iPSC) were derived from skin fibroblasts obtained from a typically developing male control who had a normal karyotype. The line is the isogenic control used to generate T2500, in which a CHD8 allele was knocked out using CRISPR/Cas9 gene editing. The two lines can be utilized by researchers interested in brain development, neurodevelopmental disorders, and cancer.
| Species | Human |
| Cat.No | ABC-SC0124T |
| Product Category | Stem Cells |
| Size/Quantity | 1 vial |
| Cell Type | Induced Pluripotent Stem Cell |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Normal |
| Biosafety Level | 2 |
| Storage | Liquid Nitrogen |
| Product Type | Human iPSCs |
For research use only
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