HighQC™ CHD8+/+ Induced Pluripotent Stem Cell

Description

HighQC™ CHD8+/+ Induced Pluripotent Stem Cells (iPSCs) are human iPSCs derived from skin fibroblasts obtained from a typically developing male donor with a normal karyotype. CHD8+/+ iPSCs exhibit typical human pluripotent stem cell morphology, forming compact, tightly packed colonies with well-defined borders, large nuclei, minimal cytoplasm, and clonal growth under adherent culture conditions. The cells were generated using integration-free reprogramming methods, such as Sendai virus–mediated delivery of defined transcription factors, to induce pluripotency. CHD8+/+ iPSCs exhibit positive expression of SSEA-4. They retain the capacity to differentiate into derivatives of all three germ layers—ectoderm, mesoderm, and endoderm—under directed differentiation conditions. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.