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Stem Cells

HighQC™ Human Esophagus Squamous Cancer Stem Cell

  • For research use only

Cat No.

ABC-SC0103
Product Type

Human Adult Stem Cells
Cell Type

Stem Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Esophagus
Disease

Esophagus Squamous Cancer
Storage

Liquid Nitrogen

Human Esophagus Squamous Cancer Stem Cell; Frozen Vial and Plated cells are available.

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  • HighQC™ Human Esophagus Squamous Cancer Stem Cell
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Home | Stem Cells | Adult Stem Cells | HighQC™ Human Esophagus Squamous Cancer Stem Cell

Description

HighQC™ Human Esophagus Squamous Cancer Stem Cells (HESCC-CSCs) are isolated from esophageal squamous cell carcinoma tissues and enriched for tumor-initiating properties. These cells exhibit a compact, spheroid morphology and express key cancer stem cell markers such as CD133, CD44, SSEA 3/4, Oct4,. They show enhanced clonogenicity, resistance to chemotherapy, and the capacity to form tumors in xenograft models. ESCC-CSCs demonstrate self-renewal and multilineage differentiation potential, contributing to tumor heterogeneity and metastasis. Gene expression profiling reveals dysregulation of Wnt/β-catenin, Hedgehog, and Notch pathways. Under differentiation cues, they can give rise to epithelial-like and mesenchymal-like lineages, making them a robust model for ESCC progression studies. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

Product Code

HighQC™ Human Esophagus Squamous Cancer Stem Cell, Human ESCC CSC, hESCC-CSC, Human Esophageal Cancer Progenitors
Species

Human
Cat.No

ABC-SC0103
Product Category

Stem Cells
Size/Quantity

1 vial
Cell Type

Stem Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Esophagus
Disease

Esophagus Squamous Cancer
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Human Adult Stem Cells

Application

  • HighQC™ Human Esophagus Squamous Cancer Stem Cells (HESCC-CSCs) are ideal for modeling esophageal squamous cell carcinoma initiation, progression, metastasis, and treatment resistance in both in vitro and in vivo systems. These cells are valuable tools for screening CSC-targeted therapies, studying epithelial-mesenchymal transition (EMT), and evaluating the role of signaling pathways in tumor maintenance. Their properties as Esophageal cancer stem cells (ESCC) also support investigation of chemotherapy resistance mechanisms, tumor recurrence, and the development of immunotherapy strategies. Their tumorigenic capability in xenografts enables patient-relevant preclinical drug evaluation and biomarker discovery for personalized oncology applications.

Citation

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
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To support a consistent result
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