HighQC™ Human IPSC-Derived Neural Stem Cell MAPT P301L HET

Description

HighQC™ Human IPSC-Derived Neural Stem Cells-MAPT P301L HET are a human iPSC-derived neural stem cell line with a heterozygous P301L mutation (CCA>CTA) introduced into the MAPT gene using CRISPR-Cas9 gene editing. One allele carries the mutation, and the other remains wild-type. These neural stem cells express typical markers of cortical neural stem and progenitor cells, such as PAX6, FOXG1, and Nestin. These MAPT P301L heterozygous iPSC-Derived NSCs are valuable for investigating targeted interventions at the preclinical stages of tauopathy. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.