HighQC™ Human IPSC From Fibroblast-Diabetes Mellitus, Juvenile-Onset Insulin-Dependent

Description

HighQC™ Human iPSCs From Fibroblasts-Diabetes Mellitus, Juvenile-Onset Insulin-Dependent, are disease-specific induced pluripotent stem cell (iPSC) lines. They were generated by reprogramming dermal fibroblasts from a donor with juvenile-onset, insulin-dependent diabetes mellitus. These cells exhibit adherent growth and retain the inherent capacity to differentiate into cell types representing all three primary germ layers (ectoderm, mesoderm, and endoderm) under defined conditions, and maintain pancreatic lineage differentiation potential to support studies on juvenile diabetes mechanisms and β-cell function. This diabetic fibroblast-derived iPSCs express the key pluripotency-associated marker SSEA-4. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.