HighQC™ Human iPSC From Fibroblast-Sporadic Alzheimer Disease

Description

HighQC™ Human iPSC from Fibroblast – Sporadic Alzheimer’s Disease was generated from human dermal fibroblasts of a sporadic Alzheimer’s disease donor and reprogrammed using retroviral delivery of Oct3/4, Sox2, Klf4, and c-Myc. The cells display stable ESC-like morphology, maintain a normal karyotype, and express key pluripotency markers. They readily form embryoid bodies (EBs) and demonstrate robust differentiation capacity into neuronal lineages, providing a physiologically relevant model of late-onset sporadic Alzheimer’s disease. These iPSCs enable a wide range of applications, including neurodegenerative disease research, phenotypic and mechanistic studies, high-throughput drug screening, and personalized medicine development, offering an essential tool for advancing translational neuroscience. The cells are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast and Bacteria.