HighQC™ IPSC from Fibroblast, African American, Male, Neonatal

Description

AcceGen provides Control Human Induced Pluripotent Stem (iPS) cells at low passages (p15). These pluripotent cells were generated from normal human skin fibroblasts using episomal reprogramming methods. This method allows the transient expression of human transcription factors (OCT4, SOX-2, KLF4, and c-MYC) that initiate the reprogramming process. The resulting human iPS cells (hiPSCs) were selected using morphological criteria without the use of either fluorescent markers or drug selection. These iPS cells have been tested for the expression of the pluripotency markers, including OCT4, SOX2, SSEA4, TRA-1-60, TRA-1-81, and alkaline phosphatase (AP) activity and normal male karyotype. This control human iPSC line can be used for CRISPR/Cas9 genome editing and differentiation to somatic lineages in vitro.