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Tumor Cell Lines

HSC-4

  • BSL

    1

  • 321
Squamous carcinoma.
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Product Code

HSC4

Species

Human

Cat.No

ABC-TC0420

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial-like

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Tongue

Disease

Tongue Squamous Cell Cancer

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Oral Cancer Cell Lines

Description

HSC-4
The HSC-4 cell line is a human oral squamous cell carcinoma (OSCC) cell derived from OSCC of the oral tongue tissue, exhibiting epithelial-like morphology and adherent culture properties. It is widely used for studying the molecular mechanisms of squamous cell carcinoma, drug screening, and metastatic invasion behavior (PMID: 36299321). HSC-4 can express a range of epidermal growth factors associated with tumorigenesis, which becomes a favorable tool for cancer research.
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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • The HSC-4 cell line finds valuable applications in the study of human oral cancer and the optimization of cancer therapy, which may necessitate novel therapeutic approaches. Notably, combined treatment with wild type p53 (wt-p53)-encoding adenovirus infection and X-irradiation has shown superior effectiveness in inhibiting cancer cell growth, in HSC4 cells with accumulated mutant p53. Moreover, HSC-4 is used to investigate and identify cancer stem-like cells that play crucial roles in chemoresistance, radioresistance, and metastasis, contributing to a deeper understanding of cancer progression and treatment resistance.

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