Human Articular Chondrocytes

Description

Human Articular Chondrocytes are derived from human articular cartilage. Following primary culture, these cells are cryopreserved. Human Articular Chondrocytes are involved in cartilage regeneration and repair, as well as specific gene regulation. Studies have shown that Human Articular Chondrocytes are implicated in the pathology of arthritis. These cells are characterized by cell staining for S100 and type II collagen. It is negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi.

Application

• Human Articular Chondrocytes serve as a control for cellular reprogramming and differentiation studies; enable molecular biology research on cartilage-related receptors, signaling pathways, cytokine activation, and gene regulation; model cartilage degradation in osteoarthritis/rheumatoid arthritis by studying apoptosis, cytotoxicity, and cellular responses; regulate immune responses through T cell proliferation modulation; and investigate chondrogenesis mechanisms involving growth factors and signaling pathways.