Human Cartilage Cells

Description

Human Cartilage Cells are isolated from the cartilage tissue. Following primary culture, the cells are cryopreserved. These cells express characteristic markers such as collagen type II (COL2A1), aggrecan (ACAN), and SOX9. Chondrocytes are specialized cells responsible for synthesizing and maintaining the extracellular matrix of cartilage, which is primarily composed of collagen and proteoglycans. This matrix provides cartilage with its characteristic strength and flexibility. Primary human articular chondrocytes are located within small cavities in the matrix known as lacunae and are derived from mesenchymal stem cells. They play an essential role in cartilage development, homeostasis, and repair, making them valuable for studying cartilage biology, degenerative joint diseases, and regenerative therapies. To ensure optimal cell viability and performance, repeated freeze-thaw cycles should be avoided during handling and culture. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.