Human Cardiac Stromal Cells

Description

Human Cardiac Stromal Cells (HCSC) are isolated from human heart tissue. These cells are derived from a single donor and cryopreserved at early passage. Cardiac stromal cells play crucial roles in maintaining the structural integrity of the heart, modulating electrical conduction, and participating in injury responses such as fibrosis and tissue remodeling. They are essential for studying cardiac microenvironment regulation and cell–cell interactions within the myocardium. These cells exhibit spindle-like morphology and express stromal and mesenchymal markers such as vimentin and PDGFR-α. Human Cardiac Stromal Cells serve as a valuable in vitro model for cardiovascular disease research, including myocardial infarction, fibrotic remodeling, and heart failure. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria. To ensure optimal viability and function, repeated freeze-thaw cycles should be avoided during culture and handling.