Human Carotid Artery Endothelial Cells, Adult

Description

Human Carotid Artery Endothelial Cells, Adult (HCtAEC), are primary endothelial cells isolated from healthy human carotid artery tissue and cryopreserved at early passage. These cells form the inner lining of the carotid artery and play a vital role in maintaining vascular homeostasis, regulating blood flow, and mediating inflammatory responses. HCtAECs are essential for studying endothelial cell biology, atherosclerosis, and vascular dysfunction, particularly in the context of cerebrovascular diseases such as stroke. They serve as a reliable in vitro model for investigating endothelial permeability, angiogenesis, and cellular interactions with circulating immune cells. These cells express endothelial markers such as CD31 (PECAM-1) and von Willebrand factor (vWF). The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria. Repeated freeze-thaw cycles should be avoided to maintain cell viability and integrity.