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Primary Cells

Human CD4+/CD45RA+/CD25-Naïve T Cells

  • For research use only

Cat No.

ABC-TC4003
Product Type

Immune Cells
Cell Type

T Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Bone Marrow
Disease

Normal
Storage

Liquid Nitrogen

First, NPB-CD4+ T Cells are negatively isolated using immunomagnetic CD4+ isolation kit from mononuclear cells.

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  • Human CD4+/CD45RA+/CD25-Naïve T Cells
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Home | Primary Cells | Human Primary Cells | Immune System Primary Cells | Human CD4+/CD45RA+/CD25-Naïve T Cells

Description

Human CD4+/CD45RA+/CD25− Naïve T Cells are a specific subset of T lymphocytes defined by the expression of CD4 and the CD45RA isoform of CD45, while lacking CD25 (IL-2 receptor α chain). These cells are considered naïve because they have not yet encountered their specific antigen and therefore remain in an unactivated state. Naïve CD4+ T cells are crucial for initiating primary immune responses and maintaining immune balance. Following primary isolation and culture, these cells are cryopreserved. In vitro, CD4+/CD45RA+/CD25− naïve T cells have limited proliferative capacity. It is recommended to avoid repeated freeze-thaw cycles during handling to preserve cellular integrity. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

Human CD4+/CD45RA+/CD25- Naïve T Cells, Naïve CD4+ T Cells (CD45RA+), Resting Helper T Cells, CD4+ RA+ T Lymphocytes
Species

Human
Cat.No

ABC-TC4003
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

T Cell
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Bone Marrow
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Immune Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human CD4+/CD45RA+/CD25-Naïve T Cells are critical for primary immune response initiation and immunological memory formation. These cells are used to study antigen-specific activation, lineage commitment, and naïve-to-effector transition. They are widely applied in vaccine testing, autoimmunity modeling, and T cell exhaustion studies. Their antigen-inexperienced state allows controlled stimulation in vitro for basic and applied immunology.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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