Human Dermal Fibroblasts, Neonatal

Description

Human Dermal Fibroblasts, Neonatal are primary cells isolated from neonatal foreskin or skin tissues. They exhibit the typical morphological characteristics of fibroblasts, featuring a spindle-like shape, adherent growth property, abundant cytoplasm, and a large and prominent nucleus. These cells express fibroblast markers, such as Vimentin, and are commonly used for the identification and analysis of human fibroblast markers. Functionally, they maintain the integrity and elasticity of the skin structure by secreting components including collagen, elastin, and glycosaminoglycans. Additionally, they participate in matrix remodeling, extracellular matrix secretion, and cellular signaling, serving as a valuable model for investigating mechanisms related to skin aging and fibroblast biology. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.