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Primary Cells

Human Epidermal Melanocytes-Medium

  • For research use only

Cat No.

ABC-TC3611
Product Type

Media
Cell Type

Melanocyte
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Epidermal
Disease

Normal
Storage

Liquid Nitrogen

HEM from AcceGen Research Laboratories are isolated from neonate human epidermis.

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  • Human Epidermal Melanocytes-Medium
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Home | Primary Cells | Human Primary Cells | Others | Human Epidermal Melanocytes-Medium

Description

Human Epidermal Melanocytes-Medium (HEM-medium) are adherent, spindle-shaped pigment cells derived from normal neonatal human skin obtained from healthy donors. As neural crest–origin cells, they localize to the basal epidermis and transfer melanin-filled melanosomes to keratinocytes via dendrites, contributing to skin pigmentation and UV protection. HEM-medium express characteristic melanocyte markers including NGF receptor (p75), fibronectin, MITF, TRPM1, and gp100/PMEL, confirming their functional identity in melanogenesis. Their clearly defined morphology, medium pigmentation level, and stable gene expression make them ideal for pigmentation biology, skin disease modeling, and UV-related research. Each lot undergoes rigorous screening and isolation procedures and is tested to ensure it is free from contamination by HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Medium Pigmented Epidermal Melanocytes, Medium Skin Melanocytes Human, NHEM-Medium, Human Epidermal Melanocytes Medium Type, Pigmented Melanocytes Medium
Species

Human
Cat.No

ABC-TC3611
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Melanocyte
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Epidermal
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Media
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • HEM-medium melanocytes provide a reliable model for studying moderate-level melanin synthesis, dendritic pigment transfer, and epidermal UV response. They are valuable in understanding the cellular basis of pigmentary conditions like piebaldism and vitiligo, and are suitable for use in 2D and 3D skin equivalents. HEM-medium also support the evaluation of melanogenesis-targeted drugs, depigmenting agents, and antioxidant-based skincare compounds in dermatology and cosmetic research pipelines.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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