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Primary Cells

Human Uterine Fibroblasts

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Primary Human Fibroblast Cells are pooled primary isolates from 250 individual neonatal donor foreskins. These cells were originated using Complete Serum-Free Medium Kit With AcceSup™, are available at <12 Cumulative Population Doublings (CPD) in vitro [Passage 3] and were cryopreserved in aliquots of ~1.5×10^6 cells. This vial will initiate a Passage 4 cell culture in […]
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Home | Primary Cells | Human Primary Cells | Reproductive System Primary Cells | Human Uterine Fibroblasts
Species

Human
Cat.No

ABC-TC3618
Quality Control

All cells test negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Fibroblast
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Uterus
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Female Reproductive Cells

Description

Human Uterine Fibroblasts (HUF) are primary cells isolated from human uterine wall tissue. These cells exhibit a typical spindle-shaped or star-like morphology with large, pale nuclei and transparent cytoplasm. They show high levels of vimentin, CD90 and fibroblast activation protein (FAP) expression. Functionally, HUF play important roles in extracellular matrix remodeling, particularly during uterine repair and inflammatory responses, and are implicated in pathological processes such as uterine fibroids due to their dysregulated collagen secretion and fibrotic activity.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • Human Uterine Fibroblasts (HUF) serve as a powerful tool for investigating uterine physiology and pathology. These cells are widely utilized to study extracellular matrix (ECM) remodeling mechanisms in conditions like uterine fibroids and endometriosis, where dysregulated collagen deposition drives fibrotic progression. Researchers use HUF to model hormonal interactions, particularly responses to estrogen and progesterone, which influence uterine tissue repair and inflammatory signaling. Their role in cell-cell communication also makes them valuable for co-culture systems with uterine smooth muscle or immune cells to mimic disease microenvironments.

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