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Human Villous Mesenchymal Fibroblasts

Product Name

Human Villous Mesenchymal Fibroblasts

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Cell Type


Growth Mode



1 vial

Shipping Info

Dry Ice


Liquid Nitrogen


Fibroblasts are mesenchymal cells which are derived from the embryonic mesoderm. Since tissuespecific mesenchymal cells are essential for normal organ development, the villous mesenchymal fibroblasts (VMF) have been used as a model system for studying the cellular mechanisms involved in regulating human placental growth. The VMF lie directly beneath the villous basement membrane; they synthesize HGF, CSF-1, granulocyte CSF and IL-6 and play an important role in the regulation of trophoblast growth and function. Studies have shown that paracrine interaction between placental VMF and the cytotrophoblast in anchoring sites is required for stimulating trophoblast infiltration.
Human Villous Mesenchymal Fibroblasts(HVMF) from AcceGen are isolated from human placental villi. HVMF are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HVMF are characterized by immunofluorescence with antibodies specific to fibronectin and/or CD90. HVMF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HVMF are guaranteed to further expand for 15 population doublings under the conditions provided by AcceGen.



Source Organ

Embryonic Mesoderm

Quality Control

All cells test negative for bacteria, yeast, fungi, and mycoplasma.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).


For research use only

Growth Conditions

37 ℃, 5% CO2

Product Type

Female Reproductive Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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