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Human Gout Peripheral Blood Mononuclear Cells

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Gout is a form of inflammatory arthritis that develops in some people who have high levels of uric acid in the blood.&nbsp,Clinical data may include: Medication (current and historical), Disease severity, Uric acid levels.
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Home | Primary Cells | Human Primary Cells | PBMCs | Human Gout Peripheral Blood Mononuclear Cells
Species

Human
Cat.No

ABC-TC4335
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Mononuclear Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Peripheral Blood
Disease

Gout
Storage

Liquid Nitrogen
Product Type

Diseased Human Peripheral Blood Mononuclear Cells

Description

Human Gout Peripheral Blood Mononuclear Cells (PBMCs) are mononuclear cell populations obtained from the peripheral blood of gout patients, and primariily consist of lymphocytes (T cells, B cells, NK cells) and monocytes. Morphologically, these cells are round or oval. PBMCs of gout patients participate in innate and adaptive immune responses, among which monocytes can differentiate into macrophages or dendritic cells, while abnormal activation of T cells (especially Th17 cells) can aggravate inflammatory responses. These immune disorders are closely related to the occurrence and development of gout, manifested as acute arthritis attacks and chronic tophi formation.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

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Application

  • Human Gout Peripheral Blood Mononuclear Cells can be used to study disease mechanisms and develop new anti-inflammatory therapies. They can also be widely utilized in anti-inflammatory drug screening platforms, especially to evaluate the effects of drugs such as IL-1 inhibitors (e.g., anakinra) and URAT1 inhibitors.

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