Human Gout Peripheral Blood Mononuclear Cells

Description

Human Gout Peripheral Blood Mononuclear Cells (PBMCs) are mononuclear cell populations obtained from the peripheral blood of gout patients, and primarily consist of lymphocytes (T cells, B cells, NK cells) and monocytes. Gout is a metabolic arthritis caused by hyperuricemia leading to monosodium urate (MSU) crystal deposition in joints and tissues. Morphologically, these cells are round or oval. PBMCs of gout patients participate in innate and adaptive immune responses, among which monocytes can differentiate into macrophages or dendritic cells, while abnormal activation of T cells (especially Th17 cells) can aggravate inflammatory responses. These immune disorders are closely related to the occurrence and development of gout, manifested as acute arthritis attacks and chronic tophi formation. These gout PBMC enable comprehensive study of immune cells in gout, facilitate peripheral blood mononuclear cells gout characterization, support PBMC analysis gout, and aid in identifying gout blood biomarkers through detailed immune profiling in gout.