Human Iliac Artery Endothelial Cells

Description

Human Iliac Artery Endothelial Cells (HIAECs) are primary cells isolated from the iliac artery. These cells belong to the endothelial cell lineage, which forms the inner lining of blood vessels and plays a critical role in vascular homeostasis. HIAECs exhibit a classic cobblestone-like appearance when cultured in vitro, adhering tightly to the substrate and forming a monolayer with contact inhibition. They regulate vascular permeability, blood flow, and immune responses. They participate in angiogenesis, thrombosis prevention, and leukocyte trafficking. Key molecular markers expressed by HIAECs include CD31, a well-established endothelial marker involved in cell–cell adhesion and vascular integrity. To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. The cells are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.