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Primary Cells

Human Intestinal Fibroblasts

  • For research use only

Cat No.

ABC-TC3655
Product Type

Intestinal Cells
Cell Type

Fibroblast
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Intestine
Disease

Normal
Storage

Liquid Nitrogen

Human Intestinal Fibroblasts from AcceGen Research Laboratories are isolated from human intestinal tissue.

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  • Human Intestinal Fibroblasts
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Home | Primary Cells | Human Primary Cells | Digestive System Primary Cells | Human Intestinal Fibroblasts

Description

Human Intestinal Fibroblasts (HIF) are mesenchymal cells derived from normal intestinal tissue, exhibiting spindle-shaped morphology and adherent growth. As key constituents of the intestinal lamina propria, they secrete an extracellular matrix rich in type I and III collagen, contributing to tissue integrity and repair. HIF are known to regulate immune cell infiltration and epithelial barrier homeostasis, playing essential roles in wound healing, fibrosis, and intestinal diseases such as Crohn's disease and ulcerative colitis. Regional heterogeneity in fibroblast phenotype underlies their functional specialization across different segments of the gut. HIF express mesenchymal lineage markers such as vimentin and PDGFRβ. Each lot undergoes rigorous screening and isolation procedures and is tested to ensure it is free from contamination by HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Intestinal Fibroblasts, Intestine Fibroblasts Human, HIFs, Gastrointestinal Stromal Fibroblasts, Human Gut Fibroblasts
Species

Human
Cat.No

ABC-TC3655
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Fibroblast
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Intestine
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Intestinal Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • HIF are widely used in gastrointestinal research to investigate fibroinflammatory responses, tissue remodeling, and epithelial-stromal interactions in diseases like IBD and fibrosis. These cells are ideal for modeling inflammation, testing antifibrotic compounds, and studying ECM-related signaling pathways.They are also employed in 3D gut models and co-culture systems with epithelial or immune cells to mimic in vivo microenvironments for drug screening and regenerative medicine applications.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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