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Primary Cells

Human Ovarian Microvascular Endothelial Cells

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Primary Human Ovarian Microvascular Endothelial Cells were initiated by elutriation of dispase dissociated normal ovarian tissue. These cells were originated using Complete Serum-Free Medium Kit With AcceSup™, are available at <12 Cumulative Population Doublings (CPD) in vitro [Passage 3] and were cryopreserved in aliquots of ~1.5×10^6 cells. This vial will initiate a Passage 4 cell […]
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Home | Primary Cells | Human Primary Cells | Reproductive System Primary Cells | Human Ovarian Microvascular Endothelial Cells
Species

Human
Cat.No

ABC-TC3742
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Endothelial
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Ovarian
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Female Reproductive Cells

Description

Human Ovarian Microvascular Endothelial Cells are isolated from healthy human ovaries and exhibit key endothelial characteristics. In culture, they form monolayers with a cobblestone morphology typical of endothelial cells and develop complex capillary-like networks on Matrigel. These cells express a range of endothelial-specific markers, including von Willebrand factor (vWF), Ulex europeus agglutinin (UEA)-1, CD31, and E-selectin. Additionally, they express VCAM-1, a marker of stimulated endothelial cells. RT-PCR analysis reveals the presence of vascular endothelial growth factor receptors (flt-1 and KDR) and endothelial nitric oxide synthase.

 

Why choose Human Ovarian Microvascular Endothelial Cells from AcceGen?

Choosing Human Ovarian Microvascular Endothelial Cells from AcceGen ensures high-quality, cryopreserved cells at passage one, guaranteed to expand for 10 population doublings. AcceGen also provides optimized media and reagents, all quality-tested for maximum performance, offering a comprehensive solution for in vitro culture.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • FOR RESEARCH USE ONLY

  • Human Ovarian Microvascular Endothelial Cells serve as an excellent in vitro model for studying angiogenesis, particularly in relation to microvascular endothelium. Angiogenesis is vital for various physiological processes, including organ development and tissue repair. These cells are especially useful for research into the angiogenic mechanisms within the ovary, such as the development of the corpus luteum. During this process, microvascular endothelial cells from the thecal layer invade the avascular granulosa layer to establish a capillary network, making these cells essential for investigating ovarian function and vascular dynamics in reproductive biology.

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