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Primary Cells

Human Plateable Hepatocytes From Whole Livers

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AcceGen offers an assortment of various human and non-human hepatic derived cells. These include Hepatocytes, Total Liver Cell Population (TLC), Stellates, Progenitors and Intra-hepatic biliary epithelial cells. We offer these as cryopreserved cells for convenience. Cryopreserved cells are suitable for a variety of assays including induction, toxicity, drug metabolism and systems biology. Both adherent and […]
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Species

Human

Cat.No

ABC-TC4022

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial

Cell Type

Hepatocyte

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Liver

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Hepatic Cells

Key Features

– Backed by AcceGen advanced technology
– Cryopreserved for highest viability and plating efficiency
– Quality-tested for accurate results

Description

Human Plateable Hepatocytes From Whole Livers are isolated from human liver tissues. Hepatocytes are the main parenchymal cells of the liver. These cells are human in origin, freshly isolated from whole liver tissues.They’re usually provided at passage 0 since they’re primary cells with limited culturing.These cells contain abundant Golgi apparatus and mitochondria, playing an important role in metabolism, protein synthesis and detoxification. Hepatocytes express markers like albumin and cytochrome P450 enzymes, detectable by immunostaining or enzyme activity assays.Studies have shown that in non-alcoholic fatty liver disease (NAFLD), hepatocytes undergo a series of metabolic changes such as impaired ketogenesis. They typically maintain a normal diploid karyotype, keeping their genetic shit intact.Hepatocytes also have immune functions and can produce and secrete innate immune proteins such as Complement C3, MAp19, MASP1, 2 3, and C-reactive protein (CRP).

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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • Human Plateable Hepatocytes From Whole Livers can be used to study liver-specific functions, metabolic studies, pathway identification, P450 induction, uptake and efflux transporter studies, and liver-derived pathogens. In addition, these cells can be used to evaluate human-specific drug metabolism, hepatobiliary drug transport, hepatotoxicity, and drug toxicity.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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