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Primary Cells

Human Pulmonary Artery Smooth Muscle Cells

  • For research use only

Cat No.

ABC-TC3775
Product Type

Pulmonary Cells
Cell Type

Smooth Muscle Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Pulmonary Artery
Disease

Normal
Storage

Liquid Nitrogen

HPASMC are isolated from human pulmonary artery.

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  • Human Pulmonary Artery Smooth Muscle Cells
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Home | Primary Cells | Human Primary Cells | Respiratory System Primary Cells | Human Pulmonary Artery Smooth Muscle Cells

Description

Human Pulmonary Artery Smooth Muscle Cells (hPASMCs) are primary cells isolated from the tunica media of human pulmonary arteries from healthy donors. They are elongated or triangular in shape. The cells exhibit characteristic “hill-and-valley” growth patterns and adhere strongly in culture. Supplied at early passage, they retain their contractile phenotype, expressing smooth muscle–specific markers including α-smooth muscle actin (α-SMA) and smooth muscle myosin heavy chain (SM-MHC). Functional assays confirm their calcium flux response and proliferative capacity under pathological conditions. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

HPASMC
Species

Human
Cat.No

ABC-TC3775
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Smooth Muscle Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Pulmonary Artery
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Pulmonary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Pulmonary Artery Smooth Muscle Cells (hPASMCs) representing primary human pulmonary arterial smooth muscle cells, are an essential in vitro model for studying the pathophysiology of pulmonary vascular diseases, particularly pulmonary arterial hypertension (PAH). They are widely used to investigate smooth muscle cell proliferation, migration, contractility, and extracellular matrix (ECM) remodeling in response to hypoxia, inflammation, and vasoactive agents. hPASMCs are also valuable for evaluating the vasodilatory or anti-proliferative effects of candidate drugs.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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